The anime is set on the titular Musical Note Island, where the god of music is said to reside. The island is home to "instrument animals," who are born from music energy, and have parts of their body composed of a musical instrument. One day, a witch arrives at the island. The warrior girl Cara must go on a journey to defeat the witch and win back the peace on the island. Source: ANN Note: The first five episodes had an advance airing on 30.03.2018. The regular broadcast started on 02.04.2018.