The world is overrun with a mysterious condition known as "Randolph syndrome" which causes sudden comas. Simultaneously, a massive underground realm known as "Asylum" in the South Pole was discovered & found to be the syndrome's origin. Weird creatures, unlike any on the surface, dwell there with previously unknown natural resources. To cure the Randolph syndrome (and to get rich plundering the creatures' genetic data and underground resources), people set foot in the Asylum. Source: ANN